A Priority Programme of the Deutsche Forschungsgemeinschaft

NANO-SYNCC


  • ¹ Dr. Hanns-Rudolf Paur
    Institut für Technische Chemie
    Bereich Thermische Abfallbehandlung (ITC-TAB)
    Forschungszentrum Karlsruhe GmbH (FZK)
    Eggenstein-Leopoldshafen
  • ¹ Professor Dr.-Ing. Henning Bockhorn
    Institut für Technische Chemie und Polymerchemie
    Universität Karlsruhe (TH)
    Karlsruhe
  • ¹ Dr. Harald Saathoff
    Institut für Meteorologie und Klimaforschung (IMK)
    Forschungsbereich Troposphäre (IMK-TRO)
    Universität Karlsruhe (TH)
    Eggenstein-Leopoldshafen
  • ¹ Dr. Carsten Weiss
    Institut für Toxikologie und Genetik (ITG)
    Forschungszentrum Karlsruhe GmbH
    in der Helmholtz Gemeinschaft
    Karlsruhe
  • ¹ Dr. Silvia Diabaté
    Institut für Toxikologie und Genetik (ITG)
    Forschungszentrum Karlsruhe GmbH
    in der Helmholtz Gemeinschaft
    Karlsruhe
1 Phase 1: until Decembre 2010
2 Phase 2: since January 2011
NANO-SYNCC

Nanoparticles: Synthesis, characterisation, and cellular effects

The aim of the project is to quantify the influence of the properties of metal-oxide nanoparticles (diameter, degree of agglomeration, chemical composition, surface characteristics, and coating) on the induction of cellular mechanisms which are characteristic of the response to oxidative stress and immune reactions. Within the framework of the project proposed, nanoparticles with defined composition, size distribution, and surface properties will be synthesised, transferred into an aerosol with defined size distribution, and deposited on cells via the air/liquid interface. Ultimately, the biological responses in cell systems will be quantified and the nanoparticles will be localised in the cellular compartments.

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